Abilify Special Warnings and Interactions
Abilify special warnings:
The most significant risk associated with taking Abilify is related to the
development of tardive dyskinesia. This risk increases with the cumulative
amount that has been taken over an extended period of time. Doctors usually
limit the risk by prescribing the minimum dosage possible or by using this
medication on a long-term basis only when absolutely necessary. If you develop
the symptoms of tardive dyskinesia which include involuntary muscular movements
of the mouth, tongue etc., you need to contact your physician immediately. Your
doctor may then have to discontinue your medication therapy with Abilify.
Abilify and Neuroleptic Malignant Syndrome:
On some rare occasions Abilify has been known to also cause a potentially fatal
condition called Neuroleptic Malignant Syndrome. Symptoms of NMS include high
fever, rigid muscles, irregular pulse or blood pressure, changes in heart
rhythm, rapid heartbeat, excessive perspiration, and altered mental status. If
any of these symptoms occur you need to contact your physician immediately who
will want to discontinue treatment with this medication.
Additional Precautions While Taking Abilify:
Abilify may have a sedative effect. Because it may make some people’s sleepy,
you should be cautious while operating automobiles or any other hazardous
machinery until you are absolutely certain how this medication affects your
coordination and judgment.
A few people have noted an abrupt drop in blood pressure when they stand up
which may lead to lightheadedness or dizziness which is referred to as
orthostatic hypotension. Always use Abilify with extreme caution if you have any
kind of circulatory problem or heart disease, take blood pressure medication, or
have any tendency to become dehydrated.
Abilify and Seizures:
Abilify has also been known to trigger seizures in a very small group of
patients and may even possibly interfere with an individual’s ability to
swallow. The risk of both of these conditions is obviously greater among the
If you’ve ever had a seizure, make sure you tell your physician immediately who
may want you to use Abilify with caution or to discontinue it completely.
Abilify and similar medications may also cause the body to overheat. You need to
be cautious in hot weather or when exercising in a strenuous manner and be sure
to drink plenty of liquids.
Children, Adolescents and the Elderly:
Finally, Abilify has never been tested in children or adolescents, although it
is now being prescribed at times for each of these age groups. Be very careful
to monitor children and adolescents while on this medication for serious side
effects. Also older adults obviously need to be very cautious when taking this
Adapted from the PDR pocket Guide to Prescription Drugs (6th and 9th
Editions), Consumer Reports Consumer Drug Reference and The PDR Family Guide to
Pictures of Abilify by Permission of
Additional information By Paul Susic
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