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Pristiq Information


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Pristiq: Effective


antidepressant for


Major Depressive






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Pristiq Side Effects


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Pristiq Side Effects to be Concerned About


Pristiq side effects overview:

While your specific Pristiq side effects cannot really be anticipated in advance, if any develop or change in their level of intensity you need to discuss this with your doctor immediately. Only your physician can decide if your specific Pristiq side effects may preclude you from continuing with this antidepressant medication.

Common Pristiq side effects may include:

Abnormal bleeding or bruising, anxiety, constipation, decreased sex drive, delayed orgasm and ejaculation, dilated pupils, dizziness, dry mouth, glaucoma, headache, high blood pressure, increased cholesterol and triglyceride levels, low sodium levels, seizures, serotonin syndrome (including restlessness, increased blood pressure, diarrhea, nausea, vomiting, increased body temperature, fast heartbeat, hallucinations, and loss of coordination), sleepiness, tiredness, tremor.


In addition to the Pristiq side effects, what are some possible food and drug interactions that I may need to consider?

If Pristiq is taken with other medications, you may notice that the effects of either may be increased decreased or altered in some other way. It is always important to check with your physician before combining this medication with the following drugs that may affect the central nervous system, lithium, migraine medications known as triptans, narcotic painkillers, sleep aids,  weight-loss products such as phentermine, tranquilizers, antipsychotic medicines, antidepressants that affect serotonin such as fluoxetine and paroxetine, MAOI’s, nonsteroidal anti-inflammatory drugs, blood thinners such as aspirin or warfarin, alcohol, ketoconazole and desipramine.

Are there any other concerns I should have besides the previously mentioned Pristiq side effects?

The previously described side effects of Pristiq are not the only concerns that you may have. You should never drive or operate dangerous machinery until you’re sure of how Pristiq affects you individually. You should also avoid drinking alcohol when taking this medication.   

Also, See:   Pristiq: Effective antidepressant for Major Depressive Disorder?

Information adapted from The PDR Pocket Guide to Prescription Drugs

Additional Information and webpage by Paul Susic  Ph.D. Licensed Psychologist  (Health and Geriatric Psychologist)  

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