Wellbutrin side-effects have usually been found to be much less than for most of the popular antidepressants such as Prozac, Paxil, Zoloft and many others within the medication classification of SSRI’s. The Wellbutrin side-effects of weight gain, anticholinergic symptoms (blurred vision, dry mouth, indigestion, and constipation) cardiac problems, and orthostatic hypotension (low blood pressure occurring after standing up) are also usually much less severe. The most common side-effects of Wellbutrin have been found to be restlessness, insomnia, headaches or worsening of pre-existing migraine conditions, tremor, dry mouth, agitation, confusion, rapid heartbeat, dizziness, nausea, constipation, menstrual complaints and rash.

The FDA approval of Wellbutrin was temporarily delayed because of the occurrence of seizures in some patients. However, upon further investigation it was found that seizures were primarily occurring at high dosages (usually above the current maximum recommended dose of 450 mg per day), and for individuals with a history of seizures or brain trauma, alcohol abuse, eating disorders, or when taken in conjunction with other medications which increase the risk of seizures. These problems have been reduced with new warnings and lower recommended doses.

Zyban and Wellbutrin should not be taken together as they contain the same active ingredients, which may lead to exceeding the maximum dosage and increasing the potential for seizures. Wellbutrin side-effects and seizures have also been noted when taking other medications which increase the likelihood of seizures, so always be sure to tell your doctor about any drugs you are taking before you begin taking Wellbutrin. Withdrawal from street drugs and alcohol has also been known to increase the risk of seizures.

Wellbutrin side- effects and seizures have been known to occur when interacting with anticonvulsant medications such as Dilantin (phenytoin), mood stabilizers like Tegretol (carbamazepine), phenobarbital, as well as the ulcer medication Tagamet (cimetidine). These medications have been known to alter the way the body uses or reacts to Wellbutrin. People taking medications for diseases such as Parkinson’s (L-dopa) have reported stronger side-effects when taking Wellbutrin. Finally, it is not recommended that you take Wellbutrin when taking antidepressant medications such as the monoamine oxidase inhibitors (MAOI’s).

By Paul Susic MA Licensed Psychologist Ph.D Candidate

 

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