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Zoloft Dosage: What is a safe amount? 

Zoloft Dosage Information 


zoloft dosageZoloft dosage for Depressive or Obsessive Compulsive Disorder 

The usual starting Zoloft dosage is 50 mg once a day, taken either in the morning or in the evening. Your doctor may increase the amount depending upon your response to the medication. The maximum Zoloft dosage is 200 mg in one day.

Zoloft dosage for Premenstrual Dysphoric Disorder 

Zoloft may be prescribed throughout the menstrual cycle or limited to the two weeks preceding menstruation.  The starting Zoloft dosage is 50 mg a day.  If this is insufficient the doctor may increase the amount in 50 mg steps at the start of each menstrual cycle up to the maximum of 100 milligrams per day in the 2-week regimen, or 150 mg per day in the full-cycle regimen.(During the first three days of the two-week regimen, doses are always limited to 50 mg).


Zoloft dosage for Panic Disorder and Post-Traumatic Stress Disorder

During the first week the usual Zoloft dosage is 25 mg once a day.  After that the dose increases to 50 mg once a day.  Depending upon your response, your physician may continue to increase your Zoloft dosage up to a maximum of 200 mg a day.


Zoloft dosage for Obsessive-Compulsive Disorder 

The starting Zoloft dosage for children aged 6 to 12 is 25 mg, and for adolescents aged 13 to 17, 50 mg per day.  Your physician should adjust the dose as necessary. Safety and effectiveness have not been established for children under the age of six.

Zoloft Overdosage

Any medication taken in excess of the recommended dosage can have serious consequences.  An overdose of Zoloft can be fatal.  If you suspect an overdose seek medical attention immediately.

Common symptoms of Zoloft overdose include: 

Agitation, dizziness, nausea, rapid heartbeat, sleepiness, tremor, and vomiting

Other less common symptoms include coma, stupor, fainting, convulsions, delirium, hallucinations, mania, high or low blood pressure, and slow, rapid, or irregular heartbeat. 

Information adapted from the The PDR Pocket Guide to Prescription Drugs - Sixth Edition

By Paul Susic Ph.D. Licensed Psychologist

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