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Zoloft: Side Effects of the Medication

Zoloft Side Effects: What do I need to know? 

 zoloft side effectsZoloft side effects cannot be anticipated. If any Zoloft side effects develop or change in intensity, you should notify your physician immediately.  Only your doctor will be able to tell you whether you should continue taking Zoloft. 

Zoloft side effects: Some of the more common side effects may include:

Abdominal pain, agitation, anxiety, constipation, decreased sex drive, diarrhea or loose stools, difficulty with ejaculation, dizziness, dry mouth, fatigue, gas, headache, and decreased appetite are some of the more common Zoloft side effects.  And, they also may include increased sweating, indigestion, insomnia, nausea, nervousness, rash, pain, sleepiness, sore throat, tingling or pins and needles, tremor, vision problems and vomiting.


Less common or rare Zoloft side effects may include:

Acne, allergic reaction, altered taste, back pain, blindness, breast development in males, breast pain or enlargement, breathing difficulties, bruise-like marks on the skin, cataracts, changeable emotions, chest pain, cold, clammy skin, conjunctivitis (pinkeye), coughing, difficulty breathing, difficulty swallowing, double vision, dry eyes, eye pain, fainting, feeling faint upon arising from a sitting or lying position, feeling of illness, female and male sexual problems, and fluid retention.  Other less common Zoloft side effects may include blushing, frequent urination, hair loss, heart attack, hemorrhoids, hiccups, high blood pressure, high pressure within the eye (glaucoma), hearing problems, hot flushes, impotence, inability to stay seated, increased appetite, increased salivation, increased sex drive, inflamed nasal passages, inflammation of the penis, intolerance to light, irregular heartbeat, itching, joint pains, kidney failure, lack of coordination, lack of sensation, leg cramps, menstrual problems, low blood pressure, migraine, movement problems, muscle cramps or weakness, need to urinate during the night, nosebleed, pain upon urination, prolonged erection, purplish spots on the skin, racing heartbeat, rectal hemorrhage, respiratory infection/lung problems, ringing in the ears, rolling eyes, sensitivity to light, sinus inflammation, skin eruptions or inflammation, sleepwalking, sore on tongue, speech problems, stomach and intestinal inflammation, swelling of the face and throat, swollen wrist and ankles, thirst, throbbing heartbeat, twitching, vaginal inflammation, hemorrhage or discharge, and yawning.

Zoloft side effects may also include mental or emotional symptoms such as:

Abnormal dreams or thoughts, aggressiveness, exaggerated feeling of well-being, depersonalization (unreal feeling), hallucinations, impaired concentration, memory loss, paranoia, rapid mood shifts, thoughts of harming yourself, tooth grinding, and worsening depression.

Zoloft side effects may also include the loss of several pounds for some individuals taking this medication.  This usually doesn't pose a problem, but may be a concern if your depression has already caused significant weight loss. 

In a few people, Zoloft side effects may also trigger manic or hypomanic states which include sensations of high energy, lack of need for sleep, grandiose thoughts and feelings and generally inappropriate and out-of-control behavior. 

Information from the The PDR Pocket Guide to Prescription Drugs - Sixth Edition

By Paul Susic Ph.D. Licensed Psychologist

See additional pictures of Zoloft dosages            Front Image - zoloft (SERTRALINE HYDROCHLORIDE)       


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